The Individual Approach To Pain Management


More often than not you hear people making claims about…this does this and that does that! But how often are claims actually supported by science, versus claims that are only supported by word of mouth or an individual’s experience? It has become far too normal for people to make recommendations or claims that are fallacious and are in no way supported by science… I like to call it “bro science”. This really becomes an issue when the claims people are making can be potentially damaging to the person you provide the recommendations.


Health claims on food labels are currently regulated under the 1990 nutrition labeling and education act (NLEA) and more specifically, regulation guidelines had been issued in 1994 by the US food and drug administration (FDA). The intent of these laws are manifested by the implementation of them, which are supposed to limit what claims are to be made unless otherwise backed by scientific research, Roe et al.,1999. However, today there is much debate as to whether or not these guidelines are true or followed appropriately under the regulation of the FDA. This makes you wonder what type of claims are currently being made with regards to products that are NOT regulated by the FDA, like Cannabidiol (CBD) and fitness supplements such as creatine and protein powders.


Cannabidiol (CBD) has recently exploded onto the market place targeting a wide range of demographics, and with that a flood of new content has emerged on to everyones favorite super duper scientific based platform, otherwise know as GOOGLE. Although there is tons of new research and literature that supports the use of CBD for treating pain and inflammation (if you know where to look), often times people make recommendations to replace clinically prescribed medication with CBD or to couple them together. The problem here is that there is almost no evidence that conclusively states the interactions or the adverse events that may occur while taking other medications with CBD. It is ALWAYS best to consult your physician if your are not certain about the interactions you may experience. Often times people do not take in to consideration that every single person is different and with that, so is their responses to cannabis and almost anything else.

I recently stumbled across a prime example of what NOT to do or follow if given this sort of recommendation. A person claimed that they were having an orthopedic issue with their heel and that they have been taking CBD with no therapeutic response. An individual encouraged them to INCREASE the dose! Do you see the problem here? For one, research states that there is a dose response relationship to cannabis, Hammell et al., 2016, Philpott et al., 2017, meaning that relatively little amounts will produce no therapeutic response, an optimal response would be somewhere in the middle, and a poor response could be attributed to taking too much. With that said, one should never take a personal recommendation and provide someone with that exact dosage claim. This was just a small yet significant example of the inability to acquire knowledge that is backed by science. In this case individuals should seek professional help from their physician to address the underlying condition, rather than just trying to mask a chronic issue that could potentially become lifelong if not dealt with appropriately.

When CBD is used the way it was intended it may do wonders for some people and almost nothing for others. It should be strongly encouraged that if the underlying condition is serious enough to seek medical attention, consult your physician about coupling CBD with your current treatment plan. This will help maximize the benefits of both CBD and professional treatment options. Finding the optimal dose may take some time and consistency… Be mindful of what your body is telling you, not what other bodies are telling you.


Roe B, Levy AS, Derby BM. The impact of health claims on consumer search and product evaluation outcomes: Results from FDA experimental data. J Public Policy Mark1999;

Hammell DC, Zhang LP, Ma F, et al. Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. Eur J Pain (United Kingdom)2016;

Philpott HT, O’Brien M, McDougall JJ. Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis. Pain2017;


Man suffers from chronic pain urges state legislature to reconsider CBD oil

RAPID CITY, S.D. (KOTA TV) – CBD oil has split the nation, for or against legalizing. The hemp derivative has no THC, the ingredient that gets you high.

Those for legalizing the oil feel there’s a learning curve for people against the medicinal product.

“If you suffered in pain like we probably did and you tried it and you liked it and it worked, why wouldn’t you use it,” says Dennis Schwartz, a former CBD oil user.

Schwartz suffers from back pain and was taking various prescription medications to ease the burning feeling he had in his legs.

When he was first introduced to CBD oil and heard it could be beneficial for pain, he and his wife, who suffers from diabetes, were both curious to try it.

“It just makes it easier in a sense because you don’t have to go to the doctor and get a prescription and all that kind of stuff. You can just use it at your own free will,” says Schwartz.

Since stores in Rapid City had to take CBD oil off their shelves, Schwartz and his wife no longer have access to the oil. He tells us they see a big difference.

“It’s affecting her … big time. I would say to the people that think it’s so bad, if they would have know how she was then and how she was after she took it and now back to the other way again, they would see the difference,” Schwartz explained.

One of the local shop owners who formerly sold CBD oil is planning to make a trip to Pierre to talk with state legislators.

Original Article by ABC News

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Tweedle Farms CBD Flower Review (Great CBD Flower Strains)

Tweedle Farms CBD Flower Today I will be reviewing a CBD company that sells it in it’s purest form. That company is Tweedle Farms and their product is CBD flower. Tweedle Farms has a whole assortment of strains of different flavors and cannabinoid portfolios. I …

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Nanocraft CBD Welcomes, Mason Ho

It is no secret that Mason Ho stems from a weave of Hawaiian surfing royalty, with his Dad and Uncle (Mike & Derek Ho) combining a series of triple crown and pipeline master’s victories, along with a ‘93 world title by Derek, which was the first Hawaiian world title in surfing history and his sister Coco being a world tour surfer for nothing short of a decade. Mason Ho has quickly become known not only as one of the best surfers in the world, but the most entertaining in anything ranging from 1 foot to 40 feet… the guy lives and dies SURF!

We recently did a little trip over to the North Shore of Oahu to pay Mason and Sheldon “doggy door” Paishon a little visit and welcome the boys to the NanoCraft CBD team. We got to do a few little strike missions to Masons favorite rock garden surf spots and were able to squeeze a few questions out of the barrel killa about CBD and why he stapled CBD into his daily routine.

NanoCraft- Q: When did you first start using CBD?

Mason Ho- A: I roughly started using CBD consistently around four years ago. My uncle Derek (’93 World Champ) gave me some that had a dark hash kind of look. He told me you can literally use it for ANYTHING! Its the CURE! I remember uncle Derek would put it on his face for sunscreen and I remember it made his skin look so nice and bright, like it was tightening his skin and was protecting it from the sun! He told me he was giving it to a girl he was friends with when they would go surf and she started putting it under one eye just for kicks. After a few days in a row she started noticing that the cannabis oil was starting to tighten and brighten her skin under the one eye and was extremely noticeable… After that I was SOLD!

NanoCraft- Q: What does CBD mean to you?

Mason Ho- A: It is sort of a life line now! I could not imagine doing what I’m doing now without it. I tend to feel like I am wasting time when the waves are firing and I am not taking it, that’s how CRAZY the stuff is!!  Maybe it’s just me getting a little older, but I have become super aware of my body in the past 5-10 years. I can tell if I do certain surfs or get smoked on a heavy one, I can sort of anticipate how I will be feeling the next day. CBD has made short acute little injuries almost non-existent!! Keeps me feeling young and ready! Before coming onboard with Nanocraft I did not always have tinctures available, which made me really realize how I can feel with and without it and have now come to realize how legit the stuff really is and I absolutely LOVE the flavors Nanocraft offers, a little something for EVERYONE! 

Nanocraft- Q: What is your favorite way to use CBD?

Mason Ho- A: The best is the topical salves! I LOVE being able to just apply it directly to the source of pain or inflammation and BANG! It just lights the area up! The instant gratification is such a game changer for me and has been something that screams MAGIC! haha. The dream would be to just have a big block of the stuff! I can just cover my whole body with it and eat a bunch! Just keep those cannabinoid levels high in the blood! Which is what they say is good! right? 

Nanocraft- A: I think we can agree with you on that one Mase! Welcome to the team brother we are very excited for 2019 and beyond!



Nanocraft CBD x Eli Olson

Eli Olson…there is nothing bad you can say about the guy! Born and raised on the North Shore of Oahu and like many of his close friends (Koa Rothman, Nathan Florence, John Florence 2 x World Champion and Kiron Jabour) he has finally begun to stich his name into the surfing world. However, Eli did not always have a recognizable name in surfing. In fact, Eli spent many years struggling for sponsorship and grinding him self to the point in which many athletes would throw in the towel, but that’s not Eli’s style!!  Aside from surfing he has also set out to create an additional path that parallels his surfing ability, Jiu-Jitsu!!

Eli has spent the last decade morphing himself into a brown belt beast, which seems to translate seamlessly into his surfing, explosive and hard charging. This winter Eli has already thrown himself over the ledge of a massive outer reef bomb at Log Cabins during a solo session, along with trips to Mavericks and Jaws chasing down the biggest surf on the planet!! The dude is no joke!

I had the pleasure of growing up with Eli and spent many years with him terrorizing the North Shore and watched him transform from a little grom, to the humble beast that he is today. It has been amazing to watch this guy evolve over the years. Eli currently holds a 2017 WSL (world surf league regional championship), along with a WSL win at Ala Moana bowls, a 2017 NAGA (North America Grappling Association) championship belt in the pro division and a runner-up finish in the 2018 NAGA championship.

I recently spoke with Eli after we signed him and asked what his biggest application  of CBD will be for 2019 and beyond…

Eli Olson: Im just looking to take my game to a whole new level!! And on that note we would like to officially welcome Eli Olson to the NanoCraft CBD team. 

Eli Olson, Left x Joel Tudor, Right

CBD oil sales expected to continue to increase in 2019

Bardstown’s Cannabinoid Solutions store was closed New Year’s Eve because they had a run on CBD oil during the holidays and couldn’t get more of their product.

“We were just selling it so quickly we couldn’t keep it in stock,” store employee Lisa Wooton said when the store reopened Wednesday.

During the holidays, she said, many customers were buying cannabidiol, or CBD, as Christmas presents and stocking stuffers.

“We went through a whole lot of oil,” she said.

The store’s owner, Mark Lundy, who is a franchise holder for the national chain Endo Scientific, said he sells several thousand dollars worth a month.

He sells 600-milligram vials for $40 and 1,500 mg for $90 of his organic product.

Other local retailers say their sales have also been brisk.

Rhonda Davis of Shepherdsville, who opened Cannabis Phrog on Bloomfield Road in Bardstown in May 2017, has moved it to a more high-traffic area near Walmart and opened her third store, in Lawrenceburg, in August. Her sales have probably quadrupled in the last year, she said.

Scott Lindsey, who holds the American Shaman franchise on North Third Street, is also expanding his business. His company has stores in Elizabethtown and Louisville as well as Bardstown, and he hopes to have six by March, including one in Mount Washington.

According to Statista, the online statistics portal, CBD oil sales increased from $108.1 million in 2014 to $262.2 million in 2016, and are expected to reach $813.2 million in the new year.

And CBD shops aren’t the only ones selling it. Pharmacies are getting in on the act, and even some gas stations, such as FiveStar, keep it behind the counter, along with cigarettes and lottery tickets.

Hemp, it seems, has gone mainstream.

And it’s expected that both sales and production will soar now that hemp is completely legal under the recently signed 2018 Farm Bill, which removed it from the list of Schedule I controlled substances. Kentucky farmers have been growing it since 2014 under state licenses and strict supervision.

Hemp is actually the same plant as marijuana, but it’s often referred to as a “cousin,” because it’s grown differently, for the cannabidiol, or CBD, rather than for the psychoactive agent, tetrahydrocannabinol, or THC. Hemp grown for its oil has less than .3 percent THC.

Lindsey said customers could drink every bottle of CBD oil in his store and it wouldn’t get them high.

Hemp oil is sold for its therapeutic value. Many of those who take it say it helps them with ailments including arthritis pain, anxiety and depression, migraine headaches, fibromyalgia, seizures, even Parkinson’s disease.

Lindsey is a believer. He’s a former bodybuilder who suffers from neck pain and sleep apnea, but after he started taking CBD, he said, his pain lessened and he can sleep all night without waking.

“For me, it’s like Jesus in a bottle,” he joked.

During his first trip to Kansas City, where American Shaman is based, Lindsey said he met a woman who had migraines until she started taking CBD, and they just disappeared. He also met a teenager whose anxiety was so bad she didn’t want to leave the house, but after she started taking it, she was able to work as a waitress.

“We can’t diagnose, treat or cure anything. We can’t make any claims at all,” Lindsey said,

At least not until the Food and Drug Administration does more research on it. But many of his customers return for more and tell him it works.

Davis said she’s also heard some remarkable testimonials from customers.

“It’s helped so many people,” she said.

Ben Mudd, a pharmacist at Medica, said his company also can’t make medical claims, but as a pharmacist, he recommends it based on patients’ experiences.

“We’ve seen a lot of patient success with pain, anxiety, depression” and other illnesses, he said. “We sell a ton of it.”

But he also urges caution.

“It’s not addictive. It’s not habit forming. It has very few side effects,” he said. Overall, he said, it’s a “safe supplement.”

But, he added, there is a potential for interaction with some drugs, including statins for controlling cholesterol and some chemotherapy drugs for cancer patients.

“We want to make sure that if people are using supplements, they check with their pharmacist or doctor before they start it because there are drug interactions that we’re sometimes worried about with some of our patients,” he said.

Lindsey also said he and his associates tell customers to consult their doctors before taking CBD if they have concerns.

Something else consumers should know is that CBD can cause them to fail a drug test by testing positive for marijuana because there are “trace amounts of THC” in the product, even if it isn’t enough to be intoxicating, Mudd said.

Mudd said the FDA has already approved a high-dosage CBD product, Epidiolex, as a prescription drug for epileptic seizures, but has taken a wait-and-see approach to low-dose CBD since the Farm Bill made hemp oil legal. If the agency doesn’t regulate it as a nutritional supplement, consumers who are already used to buying it over the counter will “throw a fit,” he said.

“It’s going to be an interesting year,” he said.

Original Article By Messanger Inquirer

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CBD for Depression (A Story of HOPE) And a Possible Treatment

CBD  For Depression C–B–D. Whenever I see those 3 letters used in tandem, I am piqued as to what new malady is on the horizon for this natural wonder drug to treat. Naturally, one might ask if CBD can cure one of life’s complicated dilemmas; …

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CBD, Melatonin & Sleep Disorders: The Natural Substitutes.


It has been estimated that about 50-70 million of Americans today suffer from some form of sleep related disorder and roughly 11% of individuals who have reported sleep issues suffer from sleep disturbances almost daily. Investigators have explained that both adolescents and adults that suffer from chronic insomnia may develop depression and anxiety related conditions later in life. Studies have also explained that people who suffer from sleep disorders are likely to develop issues with substance abuse, alcohol dependency and decreases in work performance.

In recent years research has focused the attention towards holistic approaches to find ways in which people can control their poor sleeping habits without pharmaceutical intervention. Research has recently been highlighting the impacts of melatonin and cannabidiol (CBD) as a natural sleep remedy and the results have been showing much promise in both animal and human models.


Research from the early 1970’s identified that melatonin is produced by the pineal gland within the brain, which plays an important role in circadian variation and sleep regulation. Normal increases in melatonin concentrations occur at night to induce sleep and little to no concentrations during the day, while cortisol levels rise to induce arousal. However, growing evidence has shown that as we age, decreases in melatonin concentrations contribute to poor sleeping patterns, which can also be identified in adolescents who experience poor circadian variation due to factors such as stress and anxiety.

A clinical review investigated both the safety and efficacy of melatonin for sleep disorders. Although the report was not conclusive as to whether or not sleep related disorders can be treated with melatonin, the authors did explain that there is some evidence to suggest that melatonin is effective in treating delayed sleep latency with short-term use. The study also explained that there is evidence to suggest that melatonin is safe with short term use, less than 3 months and can be used in moderation to naturally regulate circadian rhythm (Buscemi et al., 2005). If you are unsure about administering melatonin please consult your physician for more information on whether or not it is right for you.


Cannabidiol (CBD), one of the main constituents of cannabis has been known to possess hypnotic effects and has been identified as a natural sleep remedy that can improve overall quality of sleep by naturally regulating circadian rhythm. This response occurs by interaction with cannabinoid receptors within the central nervous system, immune system and the periphery. However, further research is needed to identify the underlying mechanisms associated with the effects of CBD on sleep regulation.


 A recent clinical review stated that individuals who ingested 160 mg/day showed that both sleep duration and quality were significantly improved without any adverse effects in relationship to the placebo and nitrazepam (5 mg). An additional study recently published found that CBD provided notable therapeutic applications on circadian rhythm and was consistent with clinical trials that state the therapeutic effects of CBD, but not THC to treat insomnia by triggering regions of the brain responsible for sleep regulation (Lafaye et al., 2018).

Although insomnia is just one of many sleep disorders, CBD has shown to have significant impacts on sleep duration and time, which has been recognized in animal and human models (Lafaye et al., 2018, Murillo-Rodríguez et al., 2006, Chagas et al., 2013). This ultimately allows the body’s natural ability to control sleep with the administration of CBD and can have significant impacts across a variety of sleep disorders. However, further research is still needed to prove these results and how CBD acts to control variations in naturally occurring cortisol and melatonin concentrations.

We identify that CBD and melatonin can have different individual subject responses in sleep patterns and sleep regulation. The literature has expressed the safety and the efficacy of both CBD and melatonin in subjects experiencing sleep deficiencies. We hope further research will be able to identify optimal dose responses of both products to maximize the therapeutic benefits of these natural remedies.


  1. Buscemi N, Vandermeer B, Hooton N, et al. Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: Meta-analysis. Br Med J2006;.
  2. Zhornitsky S, Potvin S. Cannabidiol in humans-The quest for therapeutic targets. Pharmaceuticals2012;.
  3. Lafaye, G., Desterke, C., Marulaz, L., and Benyamina, A. (2018) Cannabidiol affects circadian clock core complex and its regulation in microglia cells. Addiction Biology
  4. Murillo-Rodríguez E, Millán-Aldaco D, Palomero-Rivero M, Mechoulam R, Drucker-Colín R. Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. FEBS Lett2006;.
  5. Chagas MHN, Crippa JAS, Zuardi AW, et al. Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats. J Psychopharmacol2013;.




CBD treatment may expand in Iowa

Medical cannabidiol may soon be used to treat additional medical conditions in Iowa.

At a Feb. 8 public meeting, the Iowa Board of Medicine will discuss adding “severe, intractable pediatric autism with self-injurious or aggressive behaviors” to the conditions the oil, commonly referred to as CBD, can be used to treat.

In a public hearing Tuesday, the board reviewed two comments in favor by a physician and physician’s assistant.

“The Cannabidiol Board, which is part of the Department of Public Health, approved adding that condition. The Board of Medicine agreed with that and filed notice of these rules to add that condition for the use of medical cannabidiol for the state of Iowa,” Board of Medicine Interim Executive Director and Director of Legal Affairs Kent Nebel said Tuesday.

Last month, the Board of Medicine added ulcerative colitis to the list of conditions for which CBD can be used.

Members of the public or advocacy groups may petition the Cannabidiol Board to add conditions to the list, Nebel said. If approved, the Board of Medicine reviews the condition, acting as a backup to the Cannabidiol Board, Nebel said.

The Cannabidiol Board received a petition to add Autism Spectrum Disorder in August 2018. It was approved unanimously in November of 2018 but was modified because of ASD’s wide range of symptoms, skills and level of disability in functioning.

“Concerns expressed by some board members about potential negative effects the use of medical cannabidiol may have on the young developing brain are not applicable to children with severe, intractable autism that includes self-injurious or aggressive behaviors due to the severity of the autism symptoms and level of disability,” read minutes from November’s meeting.

The board also held a public hearing on amendments to training requirements for physicians in Iowa. Due to a bill passed last year by the legislature, the Board is required to draft rules regarding training for chronic pain management focusing on Center for Disease Control and Prevention guidelines for appropriate pain management. The Board also is amending rules on end-of-life care to better clarify which physicians need that training.

The Board of Medicine will next meet Feb. 8 at 9 a.m. at 800 SW 8th St. Suite C, Des Moines.

Original Article By Sioux City Journal

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