Holiday CBD


North America has developed a reputation that leaves health professionals pointing towards diet being the significant or even the main factor associated with increased incidence and mortality of cardiac, diabetic and inflammatory diseases in the western world. The social stigma surrounding eating and drinking has been something that has carried on through tradition for centuries, with today being no different. During the holiday season people gather together to celebrate family, friends, accomplishments and another year in the books. Research and literature has shown that the average population will change their “wanting” and “liking” of food during the holidays, which results in an increase in caloric intake that derives from less than ideal food choices.


Research and literature has shown that gastrointestinal inflammation may increase or arise in response to changes in dietary intake, such as high carbohydrate meals that would typically be consumed during the holidays, along with the additional sugary desserts that come along with it. Malabsorption of fructose (Carbs-Sugar) has been proposed as a possible cause of chronic gastrointestinal distress (Anderrson et al., 1978, Ravich et al., 1983) and malabsorption of sorbitol may cause gastrointestinal complaints in healthy subjects. Fructose and sorbitol are natural constituents of many common foods, like fruits, berries, and plants, and both are increasingly used as additives in food and soft drinks. It can be assumed that often times when foods are consumed in excess as they are during the holidays, high amounts of sugar such as fructose may cause gut distress, especially in those with a sensitive gastrointestinal tract.


Cannabidiol (CBD) appears to be a very promising compound because of its anti-inflammatory effects. Investigators have explained the results of a study that indicated CBD is a potent compound that is able to modulate gut inflammation through poorly understood mechanisms of action between the central nervous system and the gut, Filippis et al., 2011. This may have future implication that may enable future research to confirm these findings.

Although we all tend to have our goals and ambitious to eat clean and be mindful toward the foods we put in our body, it is nearly impossible to dodge the family undertaking of the holiday season. Booze, food, dessert… and everything else people enjoy through the holidays, research is aiming towards CBD as a possible avenue to reduce gut inflammation and potentially treat gastrointestinal inflammation in a clinical setting.

Happy Holidays!!


  1. Andersson DEH, Nygren A. Four cases of long-standing diar- rhoea and colic pains cured by fructose-free diet-a pathoge- netic discussion. Acta Med Scand 1978;203:87-92.
  1. Ravich WJ, Bayless TM, Thomas M. Fructose: incomplete intestinal absorption in humans. Gastroenterology 1983;84: 26-9.
  1. De Filippis D, Esposito G, Cirillo C, et al. Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis. PLoS One2011;